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Rates of appendicitis vary around the world, likely due to the forces of modernization.

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**Appendix** - There are many other unforeseen health changes that seem to be related to the forces of modernization, like the increase in rates of diabetes, Crohn’s disease, and ADHD. Those changes likely stem from all sorts of complicated genetic and environmental interactions - including changes in diet, exposure to pollution, and access to hygiene - that researchers haven’t yet figured out.


To learn more, start your googling with these keywords:
Fecalith: A stony mass of feces inside a person’s intestinal tract.
Appendix: A tube-shaped sac at the bottom of a person’s intestinal tract.
Appendicitis: A painful inflammation of the appendix.
Fiber: Plant-derived dietary material that’s resistant to certain digestive enzymes.
Tertiary Food Processing: Commercial production of food that often contains synthetic elements or an overabundance of certain salts and sugars.
“Western Diet”: A collective term for a diet high in fat, cholesterol, protein, sugar, and salt, that often involves frequent consumption of “fast food”.

If you liked this week’s video, you might also like: https://www.youtube.com/watch?v=r9amif1DQMc

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Addiss, D., Shaffer, N., Fowler, B., Tauxe, R. (1990). The epidemiology of appendicitis and appendectomy in the United States. The American Journal of Epidemiology.132:5 (910-1925). Retrieved from: https://www.ncbi.nlm.nih.gov/pubmed/2239906

Fares, A. (2014). Summer Appendicitis. Annals of Medical and Health Science Research. 4(1): 18-21. Retrieved from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952290

Ferris, M., Quan, S., Kaplan, B., Molodecky, N., Ball, C., Chernoff, G., Bhala, N., Ghosh, S., Dixon, E., Ng, S., Kaplan, G. (2017). The Global Incidence of Appendicitis: A Systematic Review of Population-based Studies. Annals of Surgery. 266:2 (237-241). Retrieved from: https://www.ncbi.nlm.nih.gov/pubmed/28288060

Kaplan, G. (2018). Personal communication. Assistant professor, The Gastrointestinal REsearch Group, University of Calgary.

Ramdass, M., Young Sing, Q., Milne, D., Mooteeram, J., and Barrow, S. (2015). Association between the appendix and the fecalith in adults. Canadian Journal of Surgery. 58 (10-14). Retrieved from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309758/

Direct download: The_Mystery_of_The_Exploding_Appendix.mp4
Category:general -- posted at: 10:17am EDT